Enabling and Realising New Technology Developments 2019

Wellcome Genome Conference Centre, Cambridge

Tuesday, 1st October 2019

This one day event, sponsored by Reliance Precision Limited, is focused on the delivery of new product innovation through collaboration and partnerships. The presenters will provide insights into new applications for high sensitivity imaging and label-free live cell analysis. There are also presentations on the collaborative journey that led to successful production of a functional prosthetic. For social media use #ERNTD2019

The event will include two parallel workshops, in the morning:

 

Mass Spectrometry

Workshop 1

Is focused on modelling Quadrupoles and vacuum chambers to improve time to market of mass spectrometry instruments, chaired by Jerry Coffey (Reliance Business Manager, Scientific Instruments)

 

Life Science Instrumentation

Workshop 2

Covers designing to cost, product miniaturisation and design for improved time to market, chaired by John Bazuin (Reliance Business Manager, Standard Components and Sub-assemblies)

 

Exhibition

This is a unique opportunity to speak with suppliers, collaborators and partners of Reliance to learn more about how they can help with your new technology developments. They will be exhibiting a variety of products and services and you will be able to find out more about Reliance’s latest motion control innovations.

There will be a panel discussion and a networking reception to bring this event to a close.

 

General Information

Parking is available onsite. There is a taxi rank at Cambridge station (11 miles, approximately 30 minutes from the venue).

Complimentary lunch and refreshments will be provided. Accommodation can be booked onsite at a discounted rate, for more details please see ‘Accommodation and Directions’ below.

 

Registration and Enquiries

To register for this free event please contact us for more details at events@reliance.co.uk. (Entry is by RSVP only).

 

The Exhibition and Exhibitors

Allectra is a leading manufacturer and supplier of High Vacuum and UHV components including custom items.

The company was founded in 2002 by two physicist entrepreneurs to bring a new approach to manufacturing high technology components to the scientific instruments market. In the last seventeen years Allectra has seen widespread adoption of its proprietary technology across multiple scientific disciplines.

Electrical feedthrough range includes Sub-D and Co-axial types alongside cables and accessories, also viewports and hardware. Allectra has three facilities with scientific and engineering capabilities, one in the UK and two in Germany, and ships worldwide.

Allectra Limited

Meridian House

Bluebell Business Estate

Sheffield Park

East Sussex

TN22 3HQ

+44 (0) 1825 721900

www.allectra.com

eg technology is an integrated product design and engineering consultancy with a talented team of engineers and designers who deliver successful and marketable products. They combine the personnel, resources, infrastructure and processes necessary to deliver a complete, integrated design service with a flexible, adaptable approach, and have the capabilities and experience to handle projects of all sizes.

By seamlessly connecting the disciplines of Industrial Design, Mechanical, Software and Electronics Engineering and developing a culture of continuous communication and co-operation, they work faster, find smarter solutions and provide clients with a flexible and responsive service.

eg technology

Farfield House

Albert Rd

Stow cum Quy

Cambridge

CB25 9AR

+44 (0) 1223 813184

www.egtechnology.co.uk

NPL is the UK’s National Measurement Institute, providing the measurement capability that underpins the UK’s prosperity and quality of life.

From new antibiotics to tackle resistance and more effective cancer treatments, to secure quantum communications and superfast 5G, technological advances must be built on a foundation of reliable measurement to succeed. Building on over a century’s worth of expertise, our science, engineering and technology provides this foundation.

We save lives, protect the environment and enable citizens to feel safe and secure, as well as support international trade and commercial innovation. As a national laboratory, our advice is always impartial and independent, meaning consumers, investors, policymakers and entrepreneurs can always rely on the work we do.

National Physical Laboratory

Hampton Road

Teddington

Middlesex

TW11 0LW

United Kingdom

+44 (0) 2089 773222

www.npl.co.uk

For more than 125 years, Pfeiffer Vacuum has been setting standards in vacuum technology. One milestone was the invention of the turbopump at Pfeiffer Vacuum more than 50 years ago. Thanks to the extensive know-how, Pfeiffer Vacuum continues to be the technology and world market leader in this field.

The extensive line of products and services ranges from vacuum pumps, measurement and analysis equipment to leak testing and ion beam technology solutions. The product range also includes flanges, valves, fittings and chambers as well as custom components and complex vacuum systems. Pfeiffer Vacuum has around 2,900 employees and over 20 subsidiaries worldwide.

Pfeiffer Vacuum Ltd.

16 Plover Close, Interchange Park

Newport Pagnell

Buckinghamshire

MK16 9PS

United Kingdom

+44 (0) 1908 500600

www.pfeiffer-vacuum.com

Phasefocus brings to multiple markets a range of products and services based on its proprietary Phasefocus Virtual Lens® – a disruptive technology that is revolutionising the performance of imaging instrumentation and bringing new user value to a wide range of analytical applications from label-free cell imaging and quantitative electron phase microscopy to ophthalmic lens metrology and beyond.

Phase Focus Limited

Electric Works

Sheffield Digital Campus

Sheffield

S1 2BJ

United Kingdom

+44 (0) 1142 866377

www.phasefocus.com

NEED metal components? YOU have found the SOLUTION

For over 25 years Qualitetch Components have led the way in manufacturing flat and formed metal components in the UK.  Our worldwide marketplace provides metal component parts into sectors such as: Aerospace, Medical Devices, Electronics, Automotive, Creative Arts, Scientific, Defence, Telecommunications, Renewable Energy and Instrumentation.

Qualitetch offer a wide range of manufacturing process methods to aid in the manufacture of metal components, including, Photo / Chemical Etching, Metal Stamping, EDM Wire erosion, CNC Machining, Laser Cutting and Associated services such as: 3D Component forming, Spot-welding, Finishing and Plating, Soldering and Assembly work.

Qualitetch Components Limited

1-3 Century Way, March

Cambridgeshire

PE15 8QW

United Kingdom

+44 (0) 1354 658787

www.qualitetch.co.uk

Reliance Precision is a specialist engineering company providing high reliability, precision electro-mechanical solutions to the pharmaceutical and life science industries. They deliver custom-built products, developed through expertise and experience in technical consultancy, applications engineering, research, development and manufacturing. The company’s close working relationships with customers are an important factor in helping them understand the issues they face.

Reliance Precision Limited

Rowley Mills

Penistone Road, Lepton

Huddersfield

HD8 0LE

United Kingdom

+44 (0) 1484 601000

www.reliance.co.uk

SpectralWorks is a leading UK based software development company dedicated to providing innovative solutions targeted for markets within the life sciences industry. With strong working relationships with most instrument manufacturers and coupled with outstanding collaborations in academia and industry, SpectralWorks have the right balance between scientific and software development expertise to provide unparalleled solutions. 

Our objective is simply to improve how software is integrated within the laboratory environment by providing the precise solutions to maximum productivity by maintaining focus on the end user, listening to their requirements and working within our ISO accredited processes.

SpectralWorks Ltd

The Heath Business and Technology Park

Runcorn, Cheshire

WA7 4EB

United Kingdom

+44 (0) 161 3272143

www.spectralworks.com

Keynote Speakers and Panel Members

Dr Brad Amos  

Founder/Director of Mesolens Ltd

Dr Brad Amos trained first as a zoologist with interests in optical physics and microscopy. After a PhD in Cambridge he moved to the MRC Laboratory of Molecular Biology in the early 80s, and joined John White, Richard Durbin and Mick Fordham in the development of the laser-scanning confocal microscope. This development was awarded a Rank Prize for Opto-Electronics in 1995 and Dr Brad Amos was elected FRS in 2007. He is a Founder/Director of Mesolens Ltd, which manufactures the Mesolens. He now collaborates with Professor Gail McConnell (Strathclyde) and Esmond Reid (Cambridge) in Mesolens development.

100 years on: Revisiting microscope lens design for the 3D imaging era

In the mid-80s biomedical science began to depend on chemically-specific fluorescent labels. Unfortunately, a fluorescing whole cell or large tissue sample showed a featureless glow, and the confocal laser-scanning microscope was developed to obtain clear ‘optical sections’. However, the confocal microscope did not work well with large specimens, because the available low-magnification objectives had depths of field of more than 30 um. The Mesolens solves this problem and is arguably the most radically different objective lens in 150 years of development: it provides sub-cellular resolution in hundreds of cubic millimetres of specimen volume.

Dr Richard Woolley   

Head of Operations and Production

Richard joined Phasefocus in 2016 to lead the company’s Operations and Production activities. He has held previous positions at QinetiQ and Thales working on advanced weapons systems until undertaking a PhD in Nanotechnology at the University of Nottingham. During his PhD Richard joined a newly formed spin out from the group that commercialised nanotechnology instrumentation. After a number of years as Technical Director Richard went back into academia to develop his own research into atomically precise engineering, utilising machine learning. He has also managed large ATi research projects into automated lean production with Airbus and GE.

Applying the ptychographic digital lens: Every cell tells a story

Greater clarity in our observations inevitably leads to a more detailed understanding of the system being investigated.  Using ptychography, a digital quantitative phase imaging (QPI) technique one can investigate large heterogenous cell populations at the single cell level.  As this QPI method is label free it can be applied to sensitive systems such as stem cells and primary cell cultures but also opens up the potential to use multiple fluorescent channels.  Here we will give an overview of the technology, its application and the hardware design that makes the imaging possible.

Florian Henss 

Head of Product Management, Pfeiffer Vacuum Germany

Born 1979, studied engineering and business administration at the TH Mittelhessen University of Applied Sciences.  He joined Pfeiffer Vacuum in 2001 and worked in the market segment R&D, responsible for European R&D customers. Since 2014 he is the head of product management Turbopumps at Pfeiffer Vacuum.

Modelling vacuum systems for improved time to market

The vacuum system requirements of modern mass spectrometry applications are very complex. They are related to performance, quality and cost. A solution based on standard components will not typically meet these requirements. In most cases a customized solution gives the best results. This presentation shows how Pfeiffer Vacuum can help with knowledge and experience in vacuum technology to model a customized vacuum system in a short time and reduce your time to market.

Mr Stephen Parker   

Prosthetist/Manager, Steeper Group 

Stephen is currently the Clinical Manager at the Portsmouth Enablement Centre and also provides R&D consultancy alongside his other duties. He has a Bachelor’s Degree and is an HCPC registered Prosthetist/Orthotist. He is a full member of the Institution of Engineering with a special interest in software/firmware development. He joined the Steeper Group in 1990 and held a number of senior roles within the Group, including Technical Director, heading the Research & Development for the development of the ‘bebionic’ hand.

Grant funded, collaborative development of a compliant prosthetic hand

Steeper currently provides prosthetic and orthotic clinical services to the NHS and the private sector and, since 1921 have manufactured prosthetic limbs and components for worldwide distribution. They were early developers of the simple myo-electrically controlled prosthetic hand, but for many years, wanted to improve form and function and produce a hand with individual digits that could conform to the shape of the item being held. To this end, they were successful in bidding for a Technology Strategy Board grant, which led to collaborative working with external specialist companies. I will give and overview of the development and an evaluation of the grant process.

Dr Caterina Minelli, PhD, CPhys

Principal Research Scientist, National Physical Laboratory

Caterina Minelli is a Principal Research Scientist at the National Physical Laboratory (NPL), the UK National Measurement Institute. Her work is devoted at developing the measurement infrastructure that supports innovation in medicine formulation and manufacturing. Caterina works with the Pharmaceutical industry, regulators and measurement experts worldwide to prioritise, develop and standardise chemical and physical analytics required to accelerate the delivery of effective therapeutics to market. 

Q&A Panel Member

 

Richard Hall

QMS Consultancy Ltd

Richard is an experienced QA professional with over 25 years’ experience of developing and manufacturing medical devices & IVD’s in a range of companies, from start-up to blue chip international healthcare businesses. He spent 5 years as Quality and Design Manager at Bio-Rad Laboratories in the UK before starting QMS Consultancy in 2014.

Richard now specialises in supporting medical device start-ups to gain ISO 13485 or MDSAP certification and to gain Regulatory approval for their devices. He has been named on two patents and has lectured at Imperial and Oxford Universities regarding Regulations and CE Marking.

Q&A Panel Member

 

Dr Karen Spink

Innovation Lead for Precision Medicine at Innovate UK

Karen is Innovation Lead for Precision Medicine at Innovate UK, responsible for supporting the commercial development of technology for early diagnosis and precise treatment of disease.

Karen has over 20 years of experience in leading collaborative R&D and the commercial translation of innovation. This includes nearly a decade at Pfizer leading emerging therapeutic programmes such as RNAi. Karen has also led consortia involving Biotech, NHS, and academic stakeholders to develop robust clinical diagnostics for non-invasive whole-genome profiling of cancerous tumours. 

Karen holds a PhD and BSc in Biochemistry & Genetics from The University of Nottingham.

Q&A Panel Member

 

Event Programme and Workshops

8:30 – 9:15

Registration and exhibition open

9:15 – 9:45

Welcoming address by Steve Woollven, Reliance Managing Director and Grace Farmiloe, PhD Researcher and 3rd Generation Family Member.

9:45 – 11:00   Workshops – Part A

Workshop A1

Mass Spectrometry

Chaired by Jerry Coffey (Reliance Business Manager, Scientific Instruments)

Modelling quadrupole mass filters for improved Time to Market presented by Rob Barton (Reliance Systems Engineering Team Leader)

Workshop A2

Life Science Instrumentation

Chaired by John Bazuin (Reliance Business Manager, Standard Components and Sub-assemblies)

Designing to cost; including discussion on the Value Analysis/Value Engineering (VAVE) framework presented by Rik Stewart (Reliance  Head of Design Engineering)

11:00 – 11:30

Coffee/tea break and exhibition

11:30 – 12:45   Workshops – Part B

Workshop B1

Mass Spectrometry

Chaired by Jerry Coffey (Reliance Business Manager, Scientific Instruments)

Modelling vacuum chambers and detectors for improved Time to Market presented by Florian Henss (Head of Product Management, Pfeiffer Vacuum, Germany)

Workshop B2

Life Science Instrumentation

Chaired by John Bazuin (Reliance Business Manager, Standard Components and Sub-assemblies)

Design for improved Time to Market and miniaturisation presented by Kevin Dyson (Reliance Standard Products Technical Lead)

12:45 – 13:45

Lunch and exhibition

13:45 – 14:30

Keynote speaker 1 – Dr Brad Amos, MRC Laboratory of Molecular Biology

100 years on: Revisiting microscope lens design for the 3D imaging era.” 25 minute presentation (5 minutes for questions)

Phase Focus Limited 10 minute ‘snap-shot’ presentation (5 minutes for questions)

Applying the Ptychographic digital lens: Every cell tells a story

14:30 – 15:00

Keynote speaker 2 – Mr Stephen Parker, Steeper Group

“Grant funded, collaborative development of a compliant prosthetic hand” 25 minutes presentation (5 minutes for questions)

15:00 – 15:30

Coffee/tea break and exhibition

15:30 – 16:00

Panel discussion – Q&A session

16:00 – 16:15

Closing plenary by Steve Woollven (Reliance Managing Director)

16:15 – 17:00

Networking reception

17:00

Exhibition close

The Reliance Team

Steve Woollven

Managing Director

 

Dr Ruth Brown

Business Manager – Life Sciences

 

Stephen Guy

Head of Life Sciences, Automation Specialist

Jerry Coffey

Business Manager – Scientific, Analytical & Medical

 

Rik Stewart

Head of Design Engineering

 

John Bazuin

Business Manager Catalogue Products

 

Kevin Dyson

Standard Products Technical Lead

 

Graham Lockwood

Business Development Engineer

 

Rob Barton

Systems Engineering Team Leader

 

Roger Barrett

Publicity Manager

 

Helen Selka

Director – Reliance RRG Family Board

 

Grace Farmiloe

PhD Researcher & 3rd Generation Family Member

 

Accommodation and Directions

Comfortable En-suite Bedrooms

With over 130 bedrooms, the accommodation facilities comprise modern and comfortable single, double, twin (two single beds), triple (one double bed, and one single bed) and disabled-access rooms, all set within a quiet and tranquil environment.

Bedrooms are set up to allow delegates to work comfortably in their rooms, with large desks, Wi-Fi, and media hubs.

Every room has:

  • free Wi-Fi
  • tea and coffee making facilities
  • iron and ironing board
  • hairdryer
  • TV/Plasma screen
  • media hub

Guests staying at the Conference Centre can also take full advantage of the residents’ bar in Hinxton Hall, which offers a selection of alcoholic and non-alcoholic drinks. (Bar opening is subject to minimum resident occupancy.)

Breakfast is included with all room bookings.

All rooms can be booked under contract as part of your event, or for individual stays a maximum of 10 can be booked through Reception. A standard 24-hour cancellation policy will apply. 

For more information on the accommodation, accessibility and to book accommodation, click here.

Hinxton Hall

Mullberry Court

Willow Court

Hinxton Hall

Mullberry Court

Willow Court

Directions By car

From the South:
Leave the M11 at junction 9 (signed A11 Newmarket) and take the first exit signed A1301 towards Cambridge. From the roundabout take the first left (about 800 m). At the next small roundabout follow the signpost left for the ‘Genome Campus’.

From the North:
Leave the M11 at junction 10 (note that M11 junction 9 is restricted and only accessible from the South). Turn left at the roundabout and straight over the next roundabout. Travel a mile or so on the A505 in the direction of Saffron Walden. At the next roundabout take the third exit (signed A1301 towards Saffron Walden). Pass two turnings to Hinxton village (these go to the village only), and take a right, at the next roundabout, signposted on to the Genome Campus.

Car sharing
We actively encourage all of our delegates and conference organisers to share journeys to and from the Campus where possible. If you are likely to be visiting the campus on a frequent basis you may also like to consider CamShare.

 

Directions By train

Whittlesford Parkway, Great Chesterford and Audley End are the closest railway stations to the Campus and these are all on the Cambridge-London Liverpool Street line.
(Please note that Whittlesford and Great Chesterford stations do not have a taxi rank or telephone: use either Cambridge or Audley End stations if a taxi has not been pre-booked.)
The journey time from London is approximately one hour.

Cambridge is the closest railway hub, it is on both the London King’s Cross and the London Liverpool Street line, and also serves trains coming from the north.

Timetables available from National Rail Enquiries.

For more information on how to get to the Wellcome Genome Centre by air and by taxi, please click here.